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교수소개 - 융합생명공학과

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  • 교수 세포공학
  • 이석찬 홈페이지 바로가기

[관심분야]

Molecular plant-geminivirus interactions Translational research : Side effect alleviation of cancer patients Antiviral protein development : Nucleic acid hydrolytic catalytic antibody

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  • 교수 단백질공학
  • 권대혁 홈페이지 바로가기

[관심분야]

Development of chemical regulators of SNARE-driven membrane fusion, and development of Botox substitutes for cosmetic and therapeutic purposes. Development of nanoperforators of viral envelope for antivirals (e.g., anti-influenza drugs) Protein engineering of industrial enzymes for improved stability, solubility and activity Recombinant protein production technologies (protein expression control, purification, refolding and protein characterization through spectroscopies)

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  • 교수 신경발생∙줄기세포학
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[관심분야]

Regulation of neural stem cells and brain development Stem cell therapy using induced pluripotent stem cells Neuropathology of brain infections and cancers

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  • 교수 생체대사공학
  • 조재열 홈페이지 바로가기

[관심분야]

Study of functional role of cell cytoskeleton in inflammatory and tumorgenic responses Understanding of signal transduction pathway in inflammatory signaling Development of anti-inflammatory and anti-cancer drugs Functional role of protein methylation in immune responses

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  • 부교수 분자생물 (발생생식학)
  • 오정수 홈페이지 바로가기
  • 031-290-7865
  • ohjs@skku.edu
  • 생명공학관62동 1층 62152호실

[관심분야]

Regulation of meiotic cell cycle: Cell division is a highly regulated process, driven by the action of cyclin-dependent kinases (Cdks) and their regulatory subunits, cyclins. Inappropriate activation of Cdk/cyclin complexes can drive unregulated cell division resulting in cell death or tumor formation. Cdk/cyclin complexes also play essential roles in a variety of cellular processes such as development and differentiation. Our lab is focused on the action of Cdk/cyclin complexes and all pathways that control or are controlled by Cdk/cyclin complexes during female meiosis. Homologous chromosome segregation and aneuploidy: Reduction of chromosome number during meiosis is essential for producing haploid gametes from diploid parental cells. This reduction is achieved by two successive rounds of chromosome segregation, meiosis I (MI) and meiosis II (MII), after a single round of DNA replication. Although MII resembles mitosis in that sister chromatids separate and segregate to different daughter cells, the pattern of chromosome segregation during MI is unique. During MI, homologous chromosomes pair and then segregate from each other. Defects in this process result in aneuploidy, leading to miscarriages, infertility and genetic disorders such as Down’s syndrome. Therefore, our lab studies the molecular mechanisms that control homologous chromosome segregation during meiosis. Control of oocyte quality: Mammalian oocytes are arrested at the prophase of the first meiosis. After LH surge, the oocytes resume meiosis. During these processes, the oocytes is subjected to various sources of damage-inducing factors, which may lead to a progressive deterioration of oocyte quality. Thus, the control of oocyte quality is critical to reproductive success and survival of a species; however, the precise mechanisms underlying this process remain elusive. Our lab is interesting in identifying the molecular mechanisms that control oocyte quality and eventually leading to identification of diagnostic markers that are predictive of oocyte quality in a clinical setting. Chromatin remodeling during fertilization: Fertilization leads to the transformation of two haploid gametes into a totipotent zygote. During this process, highly condensed chromatins are largely reorganized, preparing to initiate the transcription of embryonic genes which are essential for obtaining the pluripotency. Our lab is exploring the mechanisms of the chromatin remodeling upon fertilization and investigating the role of maternal factors in this process.

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  • 부교수 생체소재공학
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[관심분야]

Phage/peptide-based biomaterials Biomimetic materials Bioprinting Therapeutic bionanomaterials

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  • 부교수 세포생물학(피부과학)
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[관심분야]

Skin physiology & Signal transduction, Skin diseases & Immunology, Development of functional agents for abnormal skin conditions,

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  • 조교수
  • 송민경
  • 생명공학관62동 1층 62101호실
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  • 조교수
  • 전영준
  • 생명공학관62동 1층 62156호실